| Place | Name | | Affiliation | Time | | | Heat (Pl) |
|---|
| 1 | Sarah Angell | 14 | Generals Tc-Va | 4:53.94 | | | 2 (1) |
| 2 | Elianna Shwayder | 14 | Spirit of Pre Tc-Mi-Girls | 4:53.98 | | | 2 (2) |
| 3 | Lauren Chapey | 16 | Mamaroneck Tc-Ny | 4:55.41 | | | 2 (3) |
| 4 | Lainey Studebaker | 16 | Centerville Elite-OH | 4:57.88 | | | 1 (1) |
| 5 | Blair Ramsey | 16 | Greensboro Pacesetters TC | 4:58.37 | | | 2 (4) |
| 6 | Rylee Bowen | 18 | Una-Ca-Santa_rosa-Bowen | 4:58.57 | | | 1 (2) |
| 7 | Ciara Roche | 16 | Freehold Township Tc-Nj | 4:58.98 | | | 2 (5) |
| 8 | Paige Duca | 15 | Una-Ny-Rockville_cen-Duca | 4:59.87 | | | 2 (6) |
| 9 | Haley Wright | 16 | Boonsboro Tc-Md | 5:00.14 | | | 1 (3) |
| 10 | Mary Blankemeier | 17 | Una-Il-Oak_pa-Blankemeier | 5:02.01 | | | 2 (7) |
| 11 | Sarah Gwinn | 14 | Una-Sc-Ridge_spring-Gwinn | 5:02.11 | | | 1 (4) |
| 12 | Kelsey Harris | 15 | Carmel Tc-In | 5:02.33 | | | 1 (5) |
| 13 | Meggan Grams | 15 | Boonsboro Tc-Md | 5:02.82 | | | 2 (8) |
| 14 | Annie Taylor | 15 | Western Albemarle Tc-Va-Girls | 5:04.58 | | | 1 (6) |
| 15 | Haley Harris | 15 | Carmel Tc-In | 5:06.88 | | | 2 (9) |
| 16 | Morgan Ilse | 15 | War Eagles Tc-Ga | 5:10.46 | | | 1 (7) |
| 17 | Chelsea Ogindo | 16 | Westchester Striders Tc-N | 5:14.97 | | | 1 (8) |
| 18 | Brooke Turner | 16 | Fast Twitch Tc-Nc | 5:15.18 | | | 1 (9) |
| 19 | Claire Green | 14 | Una-Co-Louisville-Green | 5:17.87 | | | 2 (10) |
| 20 | Stephanie Hayes | 15 | Montclair Tc-Nj | 5:24.27 | | | 1 (10) |
| 21 | Jamie Grossman | 15 | Una-Ny-Huntingto-Grossman | 5:24.29 | | | 1 (11) |
| Alexandra Cooper | 15 | Comets Tc-Ny | DNS | | | 1 |
| Jenna Truedson | 15 | Una-Mn-Bemidji-Truedson | DNS | | | 2 |